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By blocking K+ channels, GLP-1 depolarizes the cell and causes calcium influx, and thus causes exocytosis of insulin from the beta-cell

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Co-lead author of the study Jia-Yi Wu, MD, a researcher from Huashan Hospital Fudan University in Shanghai, China, told MNT that unlike genetic predispositions, sedentary behavior is a modifiable risk factor. Our finding underscores the urgent need for behavioral and environmental changes to promote more active lifestyles, she added