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Swelling or tenderness in the legs, which could suggest a blood clot Pain that steadily worsens over time rather than improving Fever that accompanies muscle pain Any symptoms that feel severe or out of the ordinary for you GLP-1 medications also carry a boxed warning regarding a potential risk of thyroid C-cell tumors, including medullary thyroid carcinoma

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J Infect Dis 218(9):14741479 Yeoh HL et al (2017) Immunometabolic and lipidomic markers associated with the frailty index and quality of life in aging HIV+ men on antiretroviral therapy