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MHRA-licensed options available in the UK include orlistat (Xenical or Alli), semaglutide (Wegovy), and liraglutide (Saxenda), all recommended by NICE under specific clinical criteria and used alongside dietary and lifestyle changes
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According to the SCALE study, the basis for approving Saxenda, 3,731 patients administered with Saxenda 3mg for 56 six weeks lost at least 5 percent of the weight, and nearly half of them remained so for three years
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For a 180-pound target, it is 126 to 180 grams daily
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