Acknowledgments The authors sincerely thank laboratory colleague Weijuan Han for providing technical support in the determination of physiological indexes
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At $20-30 for the bac water, that's $1.30-2.00 per peptide vial in solvent cost well below the cost of any peptide it'll reconstitute, and the variable that determines whether the peptide makes it through its own use window.
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We show that GLP-1(2836) entered mouse caSMCs and ECs by macropinocytosis and activated sAC, as evidenced by the increased production of cAMP in caSMCs from WT but not sAC / mice