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11 were in the final stages of clinical trials as of June 2024 [114] Among others, Hangzhou Jiuyuan Gene Engineering, The United Laboratories, CSPC Pharmaceutical Group, Huadong Medicine (which also holds a majority stake in Jiuyuan Gene [117] ) and Sihuan Pharmaceutical were all preparing generic offerings

Genetic validation increases confidence in target biology but should be viewed as a supportive criterion rather than a prerequisite

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Multi-factorial risk scoring incorporates patient factors, medication characteristics, and procedural requirements to stratify patients into low, moderate, and high-risk categories [54]

A heavy contamination load can overwhelm the preservative capacity