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Using urinary hesperetin as a marker of dietary hesperidin, another group of researchers found those with the highest level of hesperidin intake had 32% lower risk of developing diabetes over 4.6 years compared to those with the lowest intake level (Sun 2015)

Temporarily discontinuing self-initiated supplements whilst awaiting medical review is reasonable if symptoms are troublesome, particularly if you began supplementation without confirmed deficiency

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Advanced aging concerns might warrant higher concentrations after tolerance establishment

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