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Being me (sciencey minded) I've done my own trials on myself with in-date and out-of-date ampoules and found no difference
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Our team strongly advises against it
doi: 10.3389/fnut.2023.1015046 Received 09 August 2022 Accepted 16 February 2023 Published 06 March 2023 Volume 10 - 2023 Edited by Domenico Sergi, University of Ferrara, Italy Reviewed by Tianlin Gao, Qingdao University, China
A 0.60 mL draw may be unusually large for one subcutaneous site
There are other factors which can also have an impact on absorption: B12 becomes more difficult to absorb as you age a mild deficiency is quite common in older adults
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