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This is particularly relevant given the increasing combined use of these effective drug classes.1011 Biological mechanisms The associations observed with the GLP-1 receptor agonist-SGLT-2 inhibitor combination in this study can be attributed to an additive effect resulting from their different yet complementary mechanisms of action

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When gastric emptying is delayed, these formulations spend more time in conditions they were not designed for

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However, early discontinuation is common due to cost, lack of access, and side effects