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The usual practice is for patients to simply turn up at the health centre where the nurse will have a supply of the injections which will be administered and there will be no cost incurred by the patient

This means the B12 component in a compounded semaglutide formulation is most likely to help patients who are deficient or at risk of deficiency, those eating very little, those following plant-based diets, older adults whose B12 absorption decreases with age, or those with conditions affecting B12 absorption like gastric bypass or certain GI conditions

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Patients starting semaglutide are often already on metformin or proton pump inhibitors (which block tablet absorption)