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The mechanisms are not fully understood but may involve delayed gastric emptying, activation of the area postrema in the central nervous system, changes in nutrient absorption, and altered intestinal motility [116,117,118]
Further, pregnancy rates were also observed to be similar across GLP-1 medications, with semaglutide presenting the lowest rate (3.42%) and liraglutide the highest (3.98%)
mutations in OCTN2 lead to primary carnitine deficiency (PCD), a disorder characterized by systemic carnitine depletion and associated clinical manifestations, including muscle weakness, cardiomyopathy, and infertility
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The FDA created a green list alert to flag imported GLP-1 active ingredients that may have quality concerns, the spokesperson said, but they noted that the list does not create new limits on legal compounding of drugs
