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"With growing evidence that GLP-1 analogs may help prevent or treat cognitive decline, and given that we can detect Glp1 transcripts in Alzheimer's-vulnerable regions in the mouse brain, this atlas should help guide future investigations into how GLP-1 acts on neuroinflammation, neuronal degeneration, and memory loss." The authors are transparent about the boundaries of the work

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Consistently, postmortem striatal brain tissue from three patients with PD exhibited elevated FTH1 and IL-8 expression, closely recapitulating the transcriptional profile of microglia in the in vitro model

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