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Current NICE guidance does not recommend glutathione supplementation for non-alcoholic fatty liver disease (NAFLD) and it is not part of standard NHS treatment protocols
It inhibits the ROS production and promotes the eNOS phosphorylation and NO production in a dose-dependent manner in FFA-treated HUVECs [124]
NadriTTowhidiAZeinoaldiniSRiaziGSharafiMZhandiMet al
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Vitamin E (800 IU daily) has some evidence supporting its use in non-diabetic adults with biopsy-proven NASH, but this is specialist-initiated, off-label use requiring discussion of potential risks, including increased risk of haemorrhagic stroke and prostate cancer with long-term use
doi: 10.1089/ars.2013.5801 209 YoritakaAKawajiriSYamamotoYNakaharaTAndoMHashimotoKet al
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