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Retatrutide Side Effects The Phase 2 retatrutide trial (Jastreboff et al., NEJM 2023) reported gastrointestinal adverse events as the dominant side-effect pattern, consistent with other GLP-1-class drugs
This typically happens when tirzepatide has been exposed to elevated temperatures for an extended period, has been stored outside the refrigerator for longer than the recommended timeframe , or has been exposed to direct light
The results of disproportionality analysis performed for these medications and SSIBs showed a reporting signal, and studies have suggested that individuals who use these medications may be at a higher risk of SSIBs [46]
The Future The emerging evidence adds to an impressive list of benefits associated with GLP-1 drugs
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