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Description

It peaks during the first 1-2 weeks at each new dose level and typically resolves within 4-8 weeks as receptor adaptation occurs

Naunyn-Schmiedebergs Arch Pharmacol 396:669682

Abstract Congenital hyperinsulinism (CHI) is a genetically heterogeneous disease, in which intractable, persistent hypoglycemia is induced by excessive insulin secretion and increased serum insulin concentration