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Conversely, either germline knockout or antisense oligonucleotide knockdown of FGFR4 expression in mice enhances hepatic fat oxidation, glucose metabolism, and insulin sensitivity (308310) while reducing hepatic steatosis (308, 309)

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[8] Some patients report feeling fatigued or having mild brain fog shortly after a dose, which usually resolves quickly

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Cell 173 , 10731081 (2018)