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Participants were randomized to placebo or retatrutide at 1 mg, 4 mg (dose-escalation), 4 mg (no escalation), 8 mg (escalation), 8 mg (no escalation), or 12 mg (escalation) for 48 weeks, following a slow titration protocol

doi: 10.1371/journal.ppat.1006654 129 FrisoniG

The NHS can only prescribe medicines that have a UK marketing authorisation and have been recommended by NICE

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Improved Insulin Sensitivity: L-Carnitine has been shown to improve insulin sensitivity, which can help with blood sugar control and reduce the risk of developing type 2 diabetes

Sermorelin stimulates natural growth hormone production, which complements the muscle-building and energy-enhancing effects of testosterone therapy