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2022;34(9):1234e12479
Sample size was determined based on practical considerations, prior experience with similar phase 1 study designs, and the objective of obtaining sufficient safety and pharmacokinetic data to support dose escalation decisions
Grenko et al
doi: 10.1161/atv.0000615456.97862.30 20 HendartoH.InoguchiT.MaedaY.IkedaN.ZhengJ.TakeiR.et al
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