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Disease Management and Clinical Outcomes, 4(1), 136-141
It is not currently FDA-approved in the United States but is available through compounding pharmacies under physician prescription
It is part of a complex "antioxidant network" where different nutrients help recycle and recharge one another
10.2337/db17-1385 198
The role of SGLT2i in diabetic HFpEF SGLT2i, a class of the most recent anti-hyperglycemic drugs, have demonstrated beneficial effects on cardiovascular outcomes and played an important role in DM patients with HFpEF (Table 2)
In the ATTAIN-MAINTAIN trial, 205 patients taking tirzepatide and 171 patients taking semaglutide were randomized to take orforglipron or placebo (no active drug) daily for a year
