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Upon investigation, they found that many issues stemmed from the manual dosing process
In contrast, when placed under metabolic stress with increased demand on the -cell (induced by high fat feeding and a low dose of the -cell toxin, streptozotocin), glucose tolerance did become impaired, supporting the view that paracrine GLP-1 may be required to maintain glucose homeostasis during adaptation to metabolic stress (114)
De La Haba, G
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doi: 10.1016/j.neuint.2012.11.009 Oh YS, Jun HS
PMID: 15 GolubicRMumboleHColemanRLReaRMathurRCaleyachettyRet al
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