By design, MB affects redox status in red blood cells, and if misused, it can actually cause or worsen methemoglobinemia (particularly if overdosed) or precipitate hemolysis in G6PD-deficient patients
On the other hand, NAC shows stronger reactivity towards hypochlorite and nitrogen dioxide, partially explaining its direct antioxidant effects against exogenous factors like diet, air pollution, or certain inflammatory conditions (Meyer et al., 1994
Can glutathione depletion cause brain fog and fatigue
PMID 9174360
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Freites-Martinez A, Santana N, Arias-Santiago S, Viera A