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In this study, we investigated the effects of dysregulated glutathione homeostasis, a principal feature of oxidative stress, on TNF-induced hepatotoxicity and its mechanistic implications in NAFLD progression

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Foods rich in antioxidants include: Berries: blueberries, strawberries, raspberries, and blackberries Dark chocolate Nuts: pecans, walnuts, pistachios Beans: kidney beans, black beans, pinto beans Vegetables: spinach, kale, broccoli, Brussels sprouts, artichoke Green tea Spices: cilantro, cinnamon, turmeric, cloves Tomatoes Red wine Avoid factors that deplete glutathione Avoid factors that deplete glutathione levels, including these: 3,4 A diet high in processed foods Alcohol Chronic diseases such as diabetes, heart disease, and cancer Excessive or prolonged physical activity Exposure to heavy metals Exposure to pollution, radiation, and environmental toxins Infections Poor nutrition Sleep deprivation Smoking Oral glutathione may not be an effective way to supplement glutathione, as digestive enzymes may break it down

This may explain why side effects are relatively rare compared to pharmaceutical approaches that introduce foreign signaling molecules

Gut Healing IBS, IBD (Crohn's and ulcerative colitis), leaky gut, NSAID-induced gut damage, and gastric/intestinal ulcers