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Bone Density Deserves Attention Rapid weight loss at any age can reduce bone mineral density, and this risk is amplified after 50 when bone density is already declining, particularly in postmenopausal women

Weeks 1 through 4: 2 mg once weekly Weeks 5 through 8: 4 mg once weekly Weeks 9 through 12: 8 mg once weekly Weeks 13 and beyond: 8 to 12 mg once weekly (based on response and tolerance) This protocol reaches the therapeutic range in approximately 8 weeks