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Tirzepatide is a dual agonist targeting GLP-1 and GIP receptors

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Calorie Restriction and IGF-1 Calorie restriction may lower IGF-1

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The answer, as we'll explore, largely depends on its state and intended duration of storage

Received: March 11, 2026 | Accepted: March 27, 2026 | Published: April 03, 2026 Abstract The treatment of type 2 diabetes and obesity has been reshaped by glucagon-like peptide-1 receptor agonists (GLP-1RAs), which produce substantial weight loss along with clear metabolic benefits