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With regard to kidney protection, in the doxorubicin (DOX) induced acute nephrotoxicity rat models, it was found that the treatment with L-theanine could attenuate the decrease of creatinine clearance, inhibit the production of lipid peroxidation in the kidney, and inhibit the reduction of glutathione content and SOD activity after DOX administration (90)
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Sies H, Belousov VV, Chandel NS, Davies MJ, Jones DP, Mann GE, et al
Cell Stem Cell, 2011