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Practical management strategies that experienced researchers use: Meal timing on escalation day: Eat a light, low-fat meal 2-3 hours before your injection

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It's gained significant attention for weight loss, though that wasn't its original purpose

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Acute illness, severe dehydration, or conditions requiring contrast dye injection may temporarily require holding metformin

If your compounding pharmacy or provider gives you a choice, consider where you are in the titration schedule