Although GSSG represents approximately 1% of the total glutathione in the cell under basal conditions, a striking increase is found in cells undergoing oxidative stress
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fumigatus , whereby Cys, GSH and SAM have become substrates for the biosynthesis of the aforementioned metabolites, along with playing a role in gliotoxin activation and attenuation, leading to unexpected consequences for fungal metabolic systems (Owens et al., 2015)
In transport epithelial cells, such as enterocytes, -glutamyl transferase ( -GT) and dipeptidase (DP) catalyzed the hydrolysis of extracellular GSH to its constituent amino acids, glutamate, cysteine and glycine
Here, we use the budding yeast Saccharomyces cerevisiae to show that cells can help each other and their future generations to survive and replicate at high temperatures
Rittes PG