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Beyond its redox coenzyme activity, NAD + serves as a substrate for sirtuins, poly(ADP-ribose) polymerases (PARPs), and other signaling enzymes that consume NAD + during the processes of DNA repair, deacetylation, and cellular stress response
PMid:32676462
Youre skipping doses on the reg
Vegans, older adults, and those on metformin or proton pump inhibitors may require B12 supplementation or monitoring
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