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Convective forces increase CXCR4-dependent glioblastoma cell invasion in GL261 murine model
Safety has improved since the FDA got oversight over bulk compounders
The most common side effect at high doses (above 1,500mg IV) is transient mild hypotension or sulfur-related gastrointestinal discomfort
doi:10.1159/000117964 Schneider-Helmert D
According to the Wegovy Summary of Product Characteristics (SmPC) , if Wegovy has been discontinued for more than two consecutive doses during the dose escalation phase, or more than two consecutive doses at any maintenance dose , treatment should generally be reinitiated at a lower dose (often 0.25 mg once weekly) and re-titrated according to clinical judgement
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