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North America leads due to strong R&D capacity, presence of major pharmaceutical players, and supportive regulatory frameworks

doi: 10.1126/sciimmunol.abm5505 214 PandayA.SahooM

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A phase II trial involving capmatinib and nabulizumab as secondary treatments for advanced/metastatic EGFR wild-type NSCLC patients, who had not received anti-PD-1/PD-L1 before, revealed that a group with elevated MET expression (evidenced by immunohistochemistry in 50% of tumor cells = 3 + or gene copy number (GCN) 5 or IHC in METex14 + = 2 +) exhibited a six-month PFS rate of 68.9%