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The reduced production of pro-inflammatory cytokines with THC administration may occur through the inhibition of NF-B signaling in microglia and astrocytes, as observed in cell culture experiments (Kozela et al., 2010

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Lipodystrophy manifests as abnormal fat distribution, marked by diminished fat in the face and limbs and increased abdominal and visceral fat, often as a side effect of antiretroviral medication