And we are not fully clear on specific mechanisms, like the black box, or potential side effects and downsides, Dillon said
GLP-1 stands for glucagon-like peptide-1, which is a hormone the body naturally produces
Across pivotal trials, nausea occurred in 42% of participants on GLP-1 agonists, 45% on dual agonists, and 50% on triple agonists, with similar patterns for vomiting and diarrhea (Table 4 and Figure 2)
Furthermore, this hormone inhibits gastric emptying, gastrointestinal motility, and glucagon secretion [9,10,11]
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10.2337/dc17-2381 42 LiuL.ShiH.XieM.SunY.NahataM