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Self-administering retatrutide outside a clinical trial carries serious risks including infection, product impurity, incorrect dosing, and lack of pharmacovigilance protection

Dosage depends on age, health condition, and the presence of additional illnesses

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Women using oral contraceptives should be counseled about this potential interaction and may need to consider alternative or additional contraceptive methods, particularly during the initial weeks of treatment when gastric emptying effects may be most pronounced

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