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Therefore, clinical testing in controlled populations is ultimately required to assess whether this preclinical efficacy is also observed in patients with CRC, both first-line in high-risk patients with high oxidative metabolic signalling (Fig
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References Bajramagic S, Sever M, Rasic F, et al
Y.et al (2001)
Mouse livers were first perfused with Krebs-Ringer buffer containing 100 M EGTA (MilliporeSigma) to chelate calcium, followed by enzymatic digestion using 60 mg of type I collagenase (Thermo Fisher Scientific) dissolved in 50 mL of DMEM/F12
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