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The following features, in isolation or combination, should prompt consideration of a possible seizure disorder and discussion with a clinician: Sudden, brief episodes of unresponsiveness or vacant staring that have a very abrupt onset and offset , particularly if they occur repeatedly and are associated with interruption of ongoing activity, may represent absence seizures. Unusual episodic sensory experiences, including odd smells, visual disturbances, a rising sensation in the abdomen or a sudden sense of fear without obvious cause, may represent focal seizure activity. Repetitive purposeless movements such as lip smacking, hand fumbling, chewing or swallowing occurring during episodes of altered awareness are associated with temporal lobe seizures

How might impaired renal function affect the clearance, dosing frequency, and efficacy of GLP-1 receptor agonists, such as semaglutide

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