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At the molecular level, Ipamorelin is a selective agonist of the GHS-R1a receptor (Growth Hormone Secretagogue Receptor 1a), also known as the ghrelin receptor

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For example, resistin-stimulated cardiac fibroblasts show increased expression of ECM proteins, including -smooth muscle actin (-SMA), COL1A1, CTGF, and fibronectin [33]

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