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self-monitor BG daily | | Sulfonylureas (glipizide, glimepiride, glyburide) | Pharmacodynamic: additive insulin release | Hypoglycemia risk | Major | Reduce sulfonylurea 50% at initiation
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Cellular GSSG accumulation, as opposed to GSH reduction, rendered hepatocytes susceptible to TNF cytotoxicity Increased GSSG/GSG ratios in response to H 2 O 2 exposure can stem from both GSH reduction and GSSG accumulation (data not shown)
LWW Journals , Tchang, Beverly G., et al
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