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doi: 10.1177/2040622315609312 59 ChristensenMKnopFKHolstJJVilsbollT

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1- surface charge-driven interaction: The positive zeta potential of PTX-CSNPs (+ 32.77 mV) promotes electrostatic binding to negatively charged components of the glomerular filtration barrier, including heparan sulfate proteoglycans in the glomerular basement membrane and the glycocalyx of proximal tubular cells, thereby prolonging renal retention