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The Synergistic effect of DNA Methylation Inhibitor 5-Azacytidine and Bcl-2 Signaling Blockade ABT-737 Combination Treatment Induce Apoptosis In AML

Ricciardi MR, Decandia S, Santinelli S, Gregorj C, De Cave F, Scerpa MC, Bergamo P, Libotte F, De Benedictis C, Vitale A, Petrucci MT, Konopleva M, Andreeff M , Milella M, Foa R, Tafuri A

The timing of the glutathione push is important because glutathione is unstable when mixed in IV bags with vitamin C and degrades over time in saline solutions

Here we summarize some of the most important achievements reached in this lively area of research

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