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Yes prolonged caloric suppression without microbial repair can reduce metabolic flexibility and lower baseline energy expenditure

CrossRef Gutliver axis dysregulation and microbial dysbiosis in invasive liver abscess: a narrative review Xiaoshuai Bai, Zhen Wang, Kai Guo, Ping Zhou, Lei Shi Frontiers in Immunology .2025;[Epub] CrossRef The role of hypothyroidism in cirrhosis pathogenesis: A retrospective cohort study and multi-omics integration analysis Ziyang Yang, Weixuan Liang, Qi Zhang, Can Weng, Hao Deng, Zhuofeng Wen, Jingyi Wu, Jingwen Deng, Zhixin Xie, Yiwei Lin, Xiuling Fu, Chengxin Gu, Tao Yang, Hui Yang, Jiyuan Zhou, Renato Polimanti PLOS Genetics .2025

"Hepatocyte-specific Gclc deletion leads to rapid onset of steatosis with mitochondrial injury and liver failure"

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Combined with our previous researches 15,16 , we concluded the penile length was improved by remodeling tunica albuginea