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Struys EA, Korman SH, Salomons GS, Darmin PS, Achouri Y, van Schaftingen E, et al

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A researcher administering 300 mcg twice daily is working with a fundamentally different pharmacokinetic profile than one administering 200 mcg three times daily, even though the total daily exposure might be similar

But understanding the math yourself means you can verify your calculations and catch errors before they happen