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Its effectiveness is likely tied to the fact that it is closely related to another holy grail skin-lightening ingredient hydroquinone

Jun SY, Sattler SA, Cortez GS, Vermerris W, Sattler SE, Kang C

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Their UV-Vis measurements suffered from significant interference caused by lipid scattering, leading to inaccurate liposome encapsulation efficiency data

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Reduced exercise performance or difficulty maintaining productivity under high demands