In a randomized, single-blind, 24-week study, participants assigned to dual therapy of 2 mg weekly of the GLP-1 receptor agonist exenatide (Bydureon, AstraZeneca) and 10 mg daily of the SGLT2 inhibitor dapagliflozin (Farxiga, AstraZeneca) lost more weight than those taking either agent alone or those receiving dapagliflozin and metformin extended-release (Xigduo XL, AstraZeneca) or phentermine/topiramate extended-release (Qsymia, Vivus)
Tirzepatide often produces faster initial results because it mimics two separate hunger hormones rather than one
The dosing of bupropion in Contrave is lower than typical antidepressant dosing, so a direct switch isnt straightforward
For example, athletes with high metabolic demands, vegans who consume no dietary B12, or individuals with chronic malabsorption issues like Crohns disease may find they feel their best with a bi-weekly (every two weeks) injection
A recent phase 3 clinical trial has unveiled a promising new therapy for managing high triglyceride levels, a major risk factor for heart disease
A generic entrant challenges that price