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Activated sulfonamides are cleaved by glutathione-S-transferases

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Accumulated benefits from consistent GH elevation begin translating into changes others can observe

A larger follow-up RCT (n=72 older adults) confirmed these findings, additionally demonstrating improvements in gait speed (+0.14 m/s), grip strength, 6-minute walk distance, waist circumference reduction, and systolic blood pressure reduction (Kumar et al., J Gerontol A Biol Sci Med Sci, 2023) [21]