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Each batch passes through Janoshik Analytical for HPLC purity quantification of each of the two component compounds and MS identity confirmation, with the minimum acceptance threshold set at 99 percent purity per component by HPLC
To determine the site of GLP-1R mediated action on BAT thermogenesis, another group performed intranuclear injections of liraglutide and determined that the ventromedial nucleus of the hypothalamus (VMH) is the specific brain region that mediates GLP-1R-induced BAT thermogenesis (Beiroa et al., 2014)
J Diabetes Invest 2014
Diabetes Ther (2015) 6(3):23956
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