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24 h) shows no toxicity to BV-2 cells at concentrations up to 4 mM after 24 h of incubation, while higher concentrations (8, 16 mM) reduce cell viability in a dose-dependent manner [5]

Factors Contributing to Vitamin B12 Deficiency Several factors can contribute to Vitamin B12 deficiency, including reduced stomach acid production in the elderly, which hinders B12 absorption from animal proteins

OA is a multifactorial disease and various risk factors of OA have been reported, such as obesity (Messier et al., 2005), and aging (Lotz and Loeser, 2012)

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