248 miR-185-5p overexpression in db/db mice that represent genetic diabetes models leads to alleviated blood hyperglycemia and decreased gluconeogenesis by directly targeting glucose-6-phosphatase (G6Pase)
This epidemiological evidence, combined with the direct presence of GLP-1 receptors in the brain, has prompted researchers to explore whether these medications might offer cognitive benefits independent of their metabolic effects
Biomolecules 5:318342 Baudouin-Cornu P, Lagniel G, Kumar C, Huang ME, Labarre J (2012) Glutathione degradation is a key determinant of glutathione homeostasis
In murine ApoE(-/-) models, GHRP-2 was associated with elevated IGF-1 levels, reduced interferon-gamma, decreased superoxide production, and modulation of inflammatory gene expression
5-Amino-1MQ increases NAD+ levels by lowering NNMT
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