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GPs and patients will need clarity on who will provide this support and how these services will be funded. NICE recommendations Semaglutide (up to a maintenance dose of 2.4 mg once weekly) can be used, within its marketing authorisation, alongside a reduced-calorie diet and increased physical activity, as an option for reducing the risk of a major adverse cardiovascular event (that is, cardiovascular death, non-fatal myocardial infarction or non-fatal stroke) in adults with both: established cardiovascular disease (CVD), defined as at least 1 of the following: previous myocardial infarction previous ischaemic or haemorrhagic stroke symptomatic peripheral arterial disease (they have intermittent claudication with an ankle-brachial index of less than 0.85 at rest, or have had a peripheral arterial revascularisation procedure or an amputation because of atherosclerotic disease), and a body mass index (BMI) of at least 27 kg/m2 Source: NICE Listen to our recent podcast episode where Pulse clinical adviser Dr Keith Hopcroft interviews Professor Ahmet Fuat, honorary professor of primary care cardiology at Durham University and GP with extended role in cardiorenal medicine, about the evidence base behind the recommendation, what the roll out might look like, who is eligible, who will be responsible for managing care, and how it fits in with existing NICE guidance on treating patients with type 2 diabetes with SGLT-2 inhibitors
The importance of glutathione in human disease
Imagine if Kleenex werent just a common name for facial tissues, but also one for snot-sucking vacuum tubes and handheld tools for picking boogers
References The information in this article is based on the following sources: Request your Quick Start Checklist for Starting or Integrating a New GLP-1 for Weight Loss Guide.
Endocrinology Scientists investigate receptor interactions and hormonal communication under controlled research conditions
And last, but certainly not least, you can also use Ros GLP-Insurance Coverage Checker , a free and accessible online tool
