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Patients should be counseled to eat smaller meals, avoid high-fat foods, and stay well-hydrated during the initial treatment period

2.5 Biochemical and Hormonal Assays Serum levels of alanine aminotransferase (ALT, B1008), aspartate aminotransferase (AST, B1058), high-density lipoprotein (HDL, B1003), low-density lipoprotein (LDL, B1004), total cholesterol (T-CHO, B1067), and triglycerides (TG, B1066) were measured using commercial kits (Nanjing Jiancheng Bioengineering Institute)

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Clinical trials show it achieves superior weight loss of up to 28.3% and significant liver fat reduction compared to single or dual agonists like semaglutide and tirzepatide

Drug interaction with medication: When initiating semaglutide, consider reducing the dose of concomitantly administered insulin secretagogue (such as sulfonylureas) or insulin to reduce the risk of hypoglycemia

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