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Its molecular mass is 873 Daltons, making it a small, stable compound that researchers have studied extensively since the early 1980s

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In PD models, no studies to date have explored the potential of irisin to modulate lactate metabolism within dopaminergic neurons

To address these limitations and improve the study design, Mendelian randomization (MR) analysis was incorporated ( 2 Methods 2.1 Study design Figure 1 provides a schematic overview of the current investigation

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