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For example, one study found that after taking 1,000 mcg of oral vitamin B12, only about 1.3% (13 mcg) is absorbed into the bloodstream

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Gastrointestinal effects are the most common and include nausea, vomiting, diarrhea, and constipation

If folate levels are low, folic acid should also be administered

Some patients receive injections on a routine schedule as part of their overall program, while others may follow a different timeline based on individual needs

[119] Physiology [edit] Absorption [edit] Vitamin B 12 is absorbed by a B 12 -specific transport proteins or via passive diffusion